Add all ingredients except the ale into a shaker with ice and shake.
Strain into a pint glass.
Top with the ale.
Garnish with a speared lemon twist.
*Ruby-red-grapefruit-infused vodka: Add 1 L vodka and 1 peeled grapefruit into a large container, seal with a lid or stopper and let stand for 3-4 days, then strain out solids.